I’m Jianghui Xiong, founder and researcher at DeepoMe , based in Beijing, China.

My work sits at the intersection of epigenetics, aging biology, and AI. Current research threads:

  • Epigenetic state quantification — DNA methylation-based biological age estimation and module-level aging clocks.
  • Biomedical world models — SteeraMed, a steerable world model for N-of-1 longevity medicine. Its core, the DNet dependency network, unifies Traditional Chinese Medicine and modern biomedicine into a single computable graph of 332 aging / chronic-disease modules.
  • AI agents for drug repurposing — SteeraMed Bench: a human-scale testbed (332 modules × 1,916 small molecules × chronic-disease tasks) for building and evaluating self-learning reasoning agents.

Preprints

Full publication list: ORCID

Elsewhere

About this blog

Short notes on preprints, aging-clock methods, and building AI tools for longevity medicine. This is the canonical home of my writing — posts appear here first and syndicate to the fediverse.